Most Recent Publications

Paper Publication: Networks of worry—towards a connectivity-based signature of late-life worry using higher criticism

Severe worry is a complex transdiagnostic phenotype independently associated with increased morbidity, including cognitive impairment and cardiovascular diseases. We investigated the neurobiological basis of worry in older adults by analyzing resting state fMRI using a large-scale network-based approach.

Read More

  • Carmen Andreescu, MD, Honored by Weill Cornell Medicine Department of Psychiatry

    We are delighted to report that Carmen Andreescu, MD (Professor of Psychiatry), has received the Weill Cornell Medicine Department of Psychiatry Perry Award, presented in memory of Samuel Wesley Perry III, MD. The Perry Award recognizes Dr. Andreescu’s exceptional program of research and mentorship that has advanced our understanding of the neural basis of depression and anxiety…

    Read More

  • Podcast: Severe Anxiety in Older Adults and its Effects Upon Brain and Body Aging

    UPMC’s Western Psychiatric Hospital’s podcast recently had Dr. Carmen Andreescu on to discuss her research on severe worry and anxiety in older adults. In the podcast, Dr. Andresscu discusses how not all worry is pathological, as well as the dramatic effects of severe worry on a patient’s psychology, brain, and aging. Intervention and treatment, as…

    Read More

  • Antonija’s Dissertation Defense

    For her dissertation, Antonija conducted an in-depth investigation into the microbiota-gut-brain axis, exploring its implications for cognitive function and depressive symptoms in older adults. The results hold promise for offering valuable insights and groundbreaking interventions for individuals facing mild cognitive impairment, dementia, and late-life depression, with the potential to alleviate their societal burden. Congratulations, Antonija!

    Read More

  • Article in the Pittsburgh Post Gazette: Brain scans can predict your age. What does this mean for healthy aging?

    ARGO’s very own Dr. Thomas Kraynak wrote an article for the Pittsburgh Post Gazette. See below for an excerpt: I wish I could have scanned my Grandma Kraynak’s brain before she died. Most people in their seventies and beyond tend to experience memory and other cognitive problems, or even develop dementia or Alzheimer’s disease. But…

    Read More

  • The American Journal of Geriatric Psychiatry: White Noise—Is Anxiety in Late-Life Associated With White Matter Hyperintensity Burden?

    Anxiety disorders are prevalent in late life, with symptoms including severe (uncontrollable) worry and rumination. Late-life anxiety, worry, and rumination in the context of the aging brain can be associated with differences in volume and thickness of gray matter regions in the brain, as well as altered functional connectivity in the networks involved in emotion…

    Read More