New Paper: MRI predictors of pharmacotherapy response in major depressive disorder
We recently published a paper, first-authored by our postdoc Dr. Andrew Gerlach, on MRI predictors of antidepressant treatment outcome. This review covers structural and functional MRI, finding that region-specific measures such as increased hippocampal volume and decreased amygdala activation to negative stimuli were the most reliable predictors, though they lacked in specificity. Though currently divergent analytical methods hinder replicability, network-based measures hold promise for capturing the underlying neurobiological mechanisms.
Click here to read the full paper.